MOTS-C 10MG

MOTS-c is a synthetic 16-amino-acid peptide research compound studied in laboratory settings for its role in mitochondrial and metabolic signaling research. As one of the first identified mitochondrial-derived peptides (MDPs), MOTS-c is examined for its interaction with cellular energy regulation and metabolic research models. Each vial from Central Peptides contains 10 mg of high-purity MOTS-c, third-party verified and supplied with a batch-specific Certificate of Analysis (COA) for research use only. As one of the most studied mitochondrial peptides, MOTS-c remains a frequently requested compound among Canadian laboratories.

MOTS-c Research Applications

MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a 16-amino-acid peptide with the sequence Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg. First described in 2015 by researchers at the University of Southern California, MOTS-c is unusual because it is encoded by mitochondrial DNA rather than nuclear DNA — its sequence is found within the 12S rRNA gene, a region not previously known to produce peptides. This unique origin places it in a new and rapidly growing category of peptide research.

In controlled laboratory environments, researchers study MOTS-c for its role as a regulator of metabolic homeostasis. Research in cells and animal models has examined its effects on glucose handling in skeletal muscle, AMPK-linked stress responses, and its movement between mitochondria and the nucleus to influence metabolic gene expression. It is frequently studied as an exercise-mimetic research tool.

Common research areas where MOTS-c is examined include:

• Mitochondrial-derived peptide (MDP) signaling research
• Glucose metabolism and insulin-sensitivity research models
• AMPK pathway and cellular stress-response studies
• Exercise-mimetic and metabolic homeostasis research

Purity and Quality Verification

Every batch of MOTS-c sold by Central Peptides is manufactured under controlled synthesis and purification processes to ensure stability, consistency, and structural integrity for scientific research applications. Our compounds are independently tested and verified at 99% purity through High-Performance Liquid Chromatography (HPLC) and mass spectrometry.

Each order includes access to a batch-specific Certificate of Analysis, allowing researchers to verify identity, purity percentage, and testing details before use. This batch-level traceability is part of our commitment to transparency and quality control across our full research catalog. Researchers who require documented purity standards for their work can review the COA before and after purchase, ensuring every vial meets the same verified specification.

Product Specifications

• Compound: MOTS-c (mitochondrial-derived peptide)
• Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (16 aa)
• Quantity: 10 mg per vial
• Purity: 99% (HPLC verified)
• Physical form: Lyophilized powder
• Lab testing: In-house HPLC and mass spectrometry
• COA: Batch-specific, available for every order
• View COA here: Lab Results | CentralPeptides.ca

Storage and Handling

MOTS-c is supplied as a lyophilized (freeze-dried) powder for maximum stability during shipping and storage. Lyophilization removes moisture from the compound, which helps preserve its structural integrity over time and allows it to remain stable during transit. For long-term integrity, store the lyophilized compound in a cool, dry environment away from light.

Once reconstituted for research, MOTS-c is soluble in water and should be kept refrigerated at 2-8°C, or at -20°C for longer-term storage. To preserve compound integrity, aliquot the reconstituted material to avoid repeated freeze-thaw cycles, and use within an appropriate window to maintain consistency in research results.

Shipping Across Canada

Central Peptides ships MOTS-c and all research compounds across Canada in discreet, temperature-conscious packaging. Orders are typically processed within 24 hours and delivered within 3 to 5 business days. Free delivery is available on qualifying orders over the threshold listed at checkout.

As a Canadian-based supplier, we offer domestic fulfillment, which means faster delivery times and fewer customs complications compared to ordering from international sources. Every shipment is packaged to protect the compound during transit and to maintain privacy.

Important Notice

• This product is intended for laboratory research and scientific purposes only.
• It is not approved by Health Canada, the FDA, or any other regulatory authority for human or veterinary use.
• This product is not intended to diagnose, treat, cure, or prevent any disease.
• By purchasing this product, customers acknowledge that it is strictly for research use only.

Buyers are responsible for conducting their own research and understanding the characteristics and intended use of this product prior to purchase.

For additional reference data on this compound, see PubChem: PubChem