Semax (10 mg) is a synthetic heptapeptide research compound derived from ACTH(4-7), studied for neuroprotection, BDNF/NGF, and neuropeptide signaling research models. Third-party tested at 99.6% purity with a batch-specific COA. Ships across Canada. For research use only — not for human consumption.
Semax is a synthetic heptapeptide research compound studied in laboratory settings for its role in neuroprotective and neuropeptide signaling research. Derived from a fragment of adrenocorticotropic hormone (ACTH), Semax is examined for its interaction with neurotrophic and gene-expression research models. Each vial from Central Peptides contains 10 mg of high-purity Semax, third-party verified and supplied with a batch-specific Certificate of Analysis (COA) for research use only. As one of the most studied nootropic research peptides, Semax remains a frequently requested compound among Canadian laboratories.
Semax Research Applications
Semax is a heptapeptide — a chain of seven amino acids — with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. Structurally, it pairs the ACTH(4-7) fragment (Met-Glu-His-Phe), the melanocortin core of adrenocorticotropic hormone, with a stabilizing Pro-Gly-Pro tail at the C-terminus. Developed in the 1980s at the Institute of Molecular Genetics of the Russian Academy of Sciences, this design is what makes Semax distinctive: the parent ACTH(4-7) fragment is cleaved within seconds by peptidases, whereas the Pro-Gly-Pro tail blocks the enzymes that would destroy it, giving Semax far greater stability.
In controlled laboratory environments, researchers study Semax for its reported transcriptional effects on brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF). It shares the same Pro-Gly-Pro stabilizing motif as its sister peptide Selank, and the two are frequently studied together in neuropeptide research.
Common research areas where Semax is examined include:
Neuroprotection and neurotrophic (BDNF, NGF) research models
Melanocortin and ACTH-fragment signaling pathways
Gene-expression and transcriptional research
Comparative research with Selank and related peptides
Purity and Quality Verification
Every batch of Semax sold by Central Peptides is manufactured under controlled synthesis and purification processes to ensure stability, consistency, and structural integrity for scientific research applications. Our compounds are independently tested and verified at 99.6% purity through High-Performance Liquid Chromatography (HPLC) and mass spectrometry.
Each order includes access to a batch-specific Certificate of Analysis, allowing researchers to verify identity, purity percentage, and testing details before use. This batch-level traceability is part of our commitment to transparency and quality control across our full research catalog. Researchers who require documented purity standards for their work can review the COA before and after purchase, ensuring every vial meets the same verified specification.
Semax is supplied as a lyophilized (freeze-dried) powder for maximum stability during shipping and storage. Lyophilization removes moisture from the compound, which helps preserve its structural integrity over time and allows it to remain stable during transit. For long-term integrity, store the lyophilized compound in a cool, dry environment away from light.
Once reconstituted for research, Semax is readily soluble in water and should be kept refrigerated at 2-8°C. To preserve compound integrity, aliquot the reconstituted material to avoid repeated freeze-thaw cycles, and use within an appropriate window to maintain consistency in research results.
Shipping Across Canada
Central Peptides ships Semax and all research compounds across Canada in discreet, temperature-conscious packaging. Orders are typically processed within 24 hours and delivered within 3 to 5 business days. Free delivery is available on qualifying orders over the threshold listed at checkout.
As a Canadian-based supplier, we offer domestic fulfillment, which means faster delivery times and fewer customs complications compared to ordering from international sources. Every shipment is packaged to protect the compound during transit and to maintain privacy.
Important Notice
This product is intended for laboratory research and scientific purposes only.
It is not approved by Health Canada, the FDA, or any other regulatory authority for human or veterinary use.
This product is not intended to diagnose, treat, cure, or prevent any disease.
By purchasing this product, customers acknowledge that it is strictly for research use only.
Buyers are responsible for conducting their own research and understanding the characteristics and intended use of this product prior to purchase.
For additional reference data on this compound, see PubChem: PubChem.
Molecular Weight
813.94 g/mol
Chemical Formula
C₃₇H₅₁N₉O₁₀
Sequence Length
7 amino acids
Peptide Structure
Met–Glu–His–Phe–Pro–Gly–Pro
Appearance
White to off-white lyophilized powder
Purity
≥99% (HPLC)
Formulation
Lyophilized peptide powder, no additives
Solubility
Soluble in bacteriostatic water or sterile water for research preparation
Stability During Shipping
Stable at room temperature for short periods due to lyophilization
