TB-500 5 MG

TB-500 is a synthetic peptide research compound studied in laboratory settings for its role in cell migration, angiogenesis, and tissue-repair research. It is the synthetic form of Thymosin Beta-4, a naturally occurring peptide involved in cytoskeletal regulation. Each vial from Central Peptides contains 5 mg of high-purity TB-500, third-party verified and supplied with a batch-specific Certificate of Analysis (COA) for research use only. As one of the most studied regenerative research peptides, TB-500 remains a frequently requested compound among Canadian laboratories.

TB-500 Research Applications

TB-500 is the synthetic form of Thymosin Beta-4, a 43-amino-acid peptide. The naturally occurring version was first isolated from calf thymus tissue in the 1960s during research into thymus gland extracts. Structurally, Thymosin Beta-4 is an unstructured, highly flexible peptide in solution, meaning it does not fold into a fixed three-dimensional shape the way many larger proteins do. It contains a central actin-binding domain — the LKKTETQ motif at residues 17-23 — which is structurally complementary to actin, one of the most common structural proteins in biology.

In controlled laboratory environments, researchers study TB-500 for its role in G-actin sequestration, which influences cytoskeletal dynamics and cell migration. Its relatively low molecular weight and unstructured nature allow it to travel through tissues, making it a widely used tool in cell-migration and angiogenesis research models.

Common research areas where TB-500 is examined include:

• Cell migration and cytoskeletal (actin) regulation research
• Angiogenesis and new blood vessel formation research
• Tissue repair and regeneration research models
• Comparative research with BPC-157 and other repair peptides

Purity and Quality Verification

Every batch of TB-500 sold by Central Peptides is manufactured under controlled synthesis and purification processes to ensure stability, consistency, and structural integrity for scientific research applications. Our compounds are independently tested and verified at 98.9% purity through High-Performance Liquid Chromatography (HPLC) and mass spectrometry.

Each order includes access to a batch-specific Certificate of Analysis, allowing researchers to verify identity, purity percentage, and testing details before use. This batch-level traceability is part of our commitment to transparency and quality control across our full research catalog. Researchers who require documented purity standards for their work can review the COA before and after purchase, ensuring every vial meets the same verified specification.

Product Specifications

• Compound: TB-500 (Thymosin Beta-4)
• Structure: 43-amino-acid peptide, actin-binding LKKTETQ domain
• Quantity: 5 mg per vial
• Purity: 98.9% (HPLC verified)
• Physical form: Lyophilized powder
• Lab testing: In-house HPLC and mass spectrometry
• COA: Batch-specific, available for every order
• View COA here: Lab Results | CentralPeptides.ca

Storage and Handling

TB-500 is supplied as a lyophilized (freeze-dried) powder for maximum stability during shipping and storage. Lyophilization removes moisture from the compound, which helps preserve its structural integrity over time and allows it to remain stable during transit. For long-term integrity, store the lyophilized compound sealed in a cool, dry environment away from light.

Once reconstituted for research, TB-500 is soluble in water and should be kept refrigerated at 2-8°C, or at -20°C for longer-term storage. To preserve compound integrity, aliquot the reconstituted material to avoid repeated freeze-thaw cycles, and use within an appropriate window to maintain consistency in research results.

Shipping Across Canada

Central Peptides ships TB-500 and all research compounds across Canada in discreet, temperature-conscious packaging. Orders are typically processed within 24 hours and delivered within 3 to 5 business days. Free delivery is available on qualifying orders over the threshold listed at checkout.

As a Canadian-based supplier, we offer domestic fulfillment, which means faster delivery times and fewer customs complications compared to ordering from international sources. Every shipment is packaged to protect the compound during transit and to maintain privacy.

Important Notice

• This product is intended for laboratory research and scientific purposes only.
• It is not approved by Health Canada, the FDA, or any other regulatory authority for human or veterinary use.
• This product is not intended to diagnose, treat, cure, or prevent any disease.
• By purchasing this product, customers acknowledge that it is strictly for research use only.

Buyers are responsible for conducting their own research and understanding the characteristics and intended use of this product prior to purchase.

For additional reference data on this compound, see PubChem: PubChem